Evaluation of Risk Factors in the development of Type 2 Diabetes and Cardiovascular disease in a Young Urban Population in Sri Lanka (LT07-108)

Main institution:
Diabetes Association of Sri Lanka (Sri Lanka)

Other institution:
King's College, London (UK)

Principal investigator:
Dr M.Wijesuriya

Other investigators:
Prof G.Viberti

Location of the project:
Sri Lanka

Amount allocated:
USD 399,670

Date:
January 1, 2008 - July 1, 2011

Objectives:
This study consists of 25,000 10 - 40 year old persons randomly selected from an urban population where 5000 persons with two or more risk factors will be identified by a simple questionnaire. They will receive biochemical and physical assessments and divided into a low intensity and high intensity life style modification and followed up for 3 years. They will receive the same screening for detection of end points. Expected outcome: Identify risk factors; Ascertain rate of incidence; Compare significance of new end points; Develop risk scores; Development of a low cost Primary Prevention strategy.

Results to date (November 2012):

- Inclusion of diabetes in National Health Policy

- Development of a project titled "Seeni Meanie" which is an innovative diabetes education and awareness campaign where schoolchildren have to formulate their own awareness campaign and educate their colleagues, teachers, parents and school community. Project is expected to reach 360 schools and approximately 1.000.000 children.

- Incorporation by the Ministry of education of Diabetes into the National School curriculum in the health and physical activity education textbooks at grade 7.

- Establishment of a Presidential task force on diabetes in collaboration with the Ministry of Health, WHO and other stakeholders.

Posters and presentations:

  • 1st Diabetes in Asia Study Group, Kathmandu (Nepal), October 2008 - (2 posters and 1 presentation)
  • 20th World Diabetes Congress, Montreal (Canada), October 2009 - (2 posters and 1 presentation)
  • 2nd Diabetes in Asia Study Group, Doha (Qatar), March 2010 - (2 posters and 1 presentation)
  • 6th World Congress on  Diabetes Prevention and its complications, Dresden (Germany), April 2010 -(1 presentation)
  • 21st World Diabetes Congress, Dubai (UAE), December 2011 (4 posters and 2 presentations)
  • 7th World Congress on diabetes prevention and its complications, Madrid (Spain), November 2012 (3 posters and 1 presentation)
  • World Diabetes Congress, Melbourne (Australia), December 2013 (5 posters)
  • 74th Annual Scientific Sessions of the American Diabetes Association, San Francisco (USA), June 2014
  • 50th EASD 2014, Vienna (Austria), September 2014
  • 2nd regional Council of South East Asia Region, Mauritius, October 2014

Publications: 

  • "DIABRISK - SL Prevention of cardio-metabolic disease with life style modification in young urban Sri Lankan's - study protocol for a randomized controlled trial", Trials 2011, 12:209
  • "High prevalence of cardio-metabolic risk factors in a young urban Sri-Lankan population", PLoS ONE 2012 
  • Network active in diabetes, newsletter 15.2012

Press release:

* Project completed in July 2011

BRIDGES (Bringing Research in Diabetes to Global Environments and Systems) is a programme initiated by the International Diabetes Federation, and supported by an educational grant from Lilly Diabetes.