Homocysteine and cardiovascular complications in diabetes

People with diabetes are prone to cardiovascular disease (CVD). In people with Type 2 diabetes, the rate of heart-related death is two to four times that in people without diabetes. Traditional risk factors for the build-up of cholesterol-rich plaques in the arteries (atherosclerosis), such as high blood pressure, obesity, smoking, and high blood fat levels (dyslipidaemia), are known to increase the cardiovascular risk in people with diabetes. However, other factors may be operative as well. In this article, Coen van Guldener and Coen Stehouwer report on raised levels of a small molecule called homocysteine in the blood (hyperhomocysteinaemia), a relatively new vascular risk factor.
CVD, cardiovascular disease, Risk factors, Homocysteine, Heart disease