Debate - the long-term safety of insulin in type 2 diabetes

More and more frequently insulin is being recommended as an ‘add-on’ to oral hypoglycaemic therapy for the achievement of blood glucose targets in people with established type 2 diabetes. Indeed, there are now trials of insulin therapy in type 2 diabetes from diagnosis. Concerns have been raised in the recent medical literature that long-term insulin therapy in type 2 diabetes increases the risk of cardiovascular disease and some cancers. We have asked specialists in the fields of clinical diabetes and pharmacoepidemiology to comment on the question:

Insulin therapy in people with type 2 diabetes: is it safe in terms of the risk of cardiovascular disease, cancer and all-cause mortality?
 


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