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  1. Towards an understanding of the genetic causes of diabetes

    People develop Type 1 diabetes when their immune system specifically seeks out and destroys the insulin-producing ß-cells in their pancreas. The interaction of environmental factors with a number of gene variants results in the immune disturbance which cau ...

    admin - 05/20/2008 - 11:23 - - Merriman Tony

  2. Pancreas and islet transplantation in the management of diabetes

    The relative roles of pancreas transplantation and islet transplantation in the management of diabetes are perhaps best examined in the context of the American Diabetes Association (ADA) position statement- revised in 2003. Given the growing success of isl ...

    admin - 05/20/2008 - 11:23 - - Robertson Paul

  3. Computer-simulated modelling in the management of diabetes

    Diabetes has many complications which can take decades to develop. Scores of therapies are now available for the prevention of Type 2 diabetes, and the complications of diabete. People with diabetes vary widely in their risks and histories of diabetes-rela ...

    admin - 05/20/2008 - 11:23 - - Brown Jonathan

  4. Bringing advanced therapies to market faster: a role for biosimulation?

    In the last 10 years, genomic and proteomic technologies have been applied to identify and develop a new generation of diabetes treatments. While these technologies have become increasingly automated, producing a deluge of potential therapeutic targets and ...

    admin - 05/20/2008 - 11:24 - - Polidori David Trimmer Jeff

  5. Homocysteine and cardiovascular complications in diabetes

    People with diabetes are prone to cardiovascular disease (CVD). In people with Type 2 diabetes, the rate of heart-related death is two to four times that in people without diabetes. Traditional risk factors for the build-up of cholesterol-rich plaques in t ...

    admin - 05/20/2008 - 11:23 - - van Guldener Coen Stehouwer Coen DA

  6. Glucagon-like peptide 1: new therapies for Type 2 diabetes

    We usually assume that the ups and downs of blood glucose are solely responsible for changes in the release of insulin into the circulation, such as in response to a meal. However, the release of insulin from the pancreas is supported by signals from the a ...

    admin - 05/20/2008 - 11:24 - - El-Ouaghlidi Andrea Nauck Michael

  7. Future directions in diabetes care: how soon is now?

    The science of diabetes is experiencing dramatic change and the implications for everyone affected by diabetes are enormous. We have good grounds for optimism and real expectations of a 'cure' for Type 1 diabetes in the longer term. This future w ...

    admin - 05/20/2008 - 11:23 - - O'Sullivan Tony

  8. Diabetic eye disease: how you can watch out for it

    Among the most feared diabetes complications are those affecting the eyes. Indeed, diabetes is the leading cause of partial vision loss and blindness in the working age population in many countries. The good news is that it does not have to be so. ...

    admin - 05/20/2008 - 11:24 - - Arun Chankramath Taylor Roy

  9. Aetiology of type 2 diabetes: the road to consensus

    In 1965, the World Health Organization (WHO) Expert Committee report on diabetes warned of the danger of an emerging diabetes epidemic. At that time, prevalence rarely exceeded 2%. Today, we know that more than 194 million people worldwide have diabetes. I ...

    admin - 05/20/2008 - 11:24 -

  10. Understanding diabetes: the genetics

    In most people who develop diabetes there is a hereditary (genetic) component. However, in nearly all cases the genetic component alone does not cause the diabetes, but interactions with the environment of a person who is genetically susceptible. This is c ...

    admin - 05/20/2008 - 11:24 - - Hitman Graham

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