Tianjin Women and Children’s Health Centre
The Chinese University of Hong Kong
Chinese Academy of Sciences
Pennington Biomedical Research Centre, USA
Xilin Yang; Fuxia Zhang; Gang Hu; Zhijie Yu; Ling Dong; Hong Zhang
Location of the project:
July 1, 2010 - December 31, 2013
We established a provincial antenatal care network to screen for gestational diabetes mellitus (GDM) in Tianjin 10 years ago but the perinatal management of women with GDM remains suboptimal. Two large randomized trials have confirmed the benefits of tight control of hyperglycaemia on maternal health and foetal outcomes. In this proposal, we aim to translate a proven GDM-care protocol to daily practice using a shared care model within the three-tier antenatal care system in Tianjin, with a randomized design. The primary outcome is reduced incidence of deliveries of babies with birth weight ≥ 4500 grams. The secondary outcomes are reduced pregnancy-induced hypertension and macrosomia.
Results to date (November 2012):
- "Can shared care improve outcomes in women with gestational diabetes?"Diabetes Voice, June 2011 
- " A randomised translational trial of lifestyle intervention using a 3-tier shared care approach on pregnancy outcomes in Chinese women with gestational diabetes mellitus but without diabetes " Journal of translational medicine, 2014, 12.290
- "Prevalence of Gestational Diabetes Mellitus and Its Risk Factors in chinese pregnant women: A Prospective Population-Based Study in Tianjin, China " PLOS ONE March 2015
- "ABO blood groups and gestational diabetes mellitus: a prospective population based study in Tianjin, China " Diabetes Metab Res Rev 2015
World Diabetes Congress, Dubai (UAE), December 20011
World Diabetes Congress, Melbourne, (Australia) December 2013
BRIDGES (Bringing Research in Diabetes to Global Environments and Systems) is a programme initiated by the International Diabetes Federation , and supported by an educational grant from Lilly Diabetes.