Insensitivity to insulin and obesity: the underlying cause

Insensitivity to insulin and obesity: the underlying cause [1]

Submitted by admin on Tue, 05/20/2008 - 11:05

In the late 20th century obesity became an epidemic. The importance of obesity as a risk factor for a number of conditions, including type 2 diabetes, cardiovascular disease, hypertension, gallstones and certain cancers, is well documented. Often associated with insensitivity to insulin, obesity is clearly a key factor in the development of the metabolic syndrome – a risk for both diabetes and cardiovascular disease. In this article, Robert Eckel and Scott Grundy explore the underlying causes of obesity and insensitivity to insulin.

Issue:

Volume 51 | Special Issue [2]

Author:

Eckel Robert [3]

Grundy Scott [4]

Attachment:

article_414_en.pdf [5]

Keywords:

insulin, obesity, cardiovascular disease, interleukin-6, IL-6, plasminogen activator inhibitor-I (PAI-I)

Section:

Health Delivery [6]

Theme:

Complications > Cardiovascular disease [7]

Insulin [8]

Obesity [9]

Metabolic syndrome [10]