Diabetes treatment


Enhancing insulin secretion: novel approaches to glucose control

When we eat, the concentration of glucose in our blood rises due to the uptake of glucose from the digestion of starch and other carbohydrates in the gut. In healthy people, the increase is modest; eating activates other processes that

Meal-time glucose control: the role of oral drugs

As a species, our condition has changed: from prolonged periods of fasting and occasional gorging, to nearly constant feeding with rarely occurring periods of fasting. The constant availability of ‘grazing opportunities’ has contributed to a change in the body build of humans towards increasing body weight, overweight, and obesity. With this change has come a massive increase in the number of people with diabetes and diabetes- and- obesity-related health problems.

Home blood glucose monitoring: a useful self-management tool

There is no doubt that the introduction of home blood glucose monitoring has helped to revolutionize diabetes management and reduce the amount of time people with diabetes need to spend in hospital to stabilize their condition. However, this has given rise to a series of compliance and management issues for the person with diabetes and the health professional who provides their care. Jan Alford reports.

The impact of low health literacy on diabetes outcome

According to the 1993 US National Adult Literacy Survey, approximately 90 million people in the USA have deficiencies in reading or computational skills that prevent them from fully participating in normal daily activities – such as reading a bus schedule or entering background information on an application form. Although the Survey did not evaluate the ability to read and comprehend health-related materials,

Understanding the psychological barriers to effective diabetes therapy

In order to minimize the risk of diabetes complications, effective therapy for people with Type 2 diabetes involves lifestyle changes and poly-pharmacy targeting levels of blood glucose, blood pressure and blood fat. However, the strict targets set in recent guidelines are seldom achieved by the majority of people with diabetes. Barriers to effective diabetes therapy have been identified within the organization of health care and in the interaction between health-care providers and people with

The other global fuel crisis

President's editorial

Psychological insulin resistance: what do patients and providers fear most?

If insulin is such an effective drug, why are so many people with type 2 diabetes reluctant to take it, and sometimes really apprehensive, despite acknowledged poor outcomes on diet and oral blood glucose lowering agents? Are healthcare providers part of the problem? Is there such syndrome as Insulin Resistance (PIR)? For a better understanding of PIR, which is commonly observed as a problem in type 2 diabetes, we need to look beyond the demonstrated efficacy of insulin, and understand people’s beliefs, emotions and concerns regarding insulin treatment.

Lessons from the history of insulin

I recently had the enormous honour to unveil a large bronze statue of Nicolae Paulescu in Bucharest together with the President of Romania. The occasion was the 80th anniversary of the publication of Paulescu’s seminal paper on his discovery of insulin…

Complementary therapies

'Complementary therapies' have been in use for thousands of years. Today they are increasingly popular with the general public and many health professionals, especially nurses and general practitioners. Despite the wide availability of conventional medications, over 50% of the populations of most Western countries use complementary therapies. This figure may be even higher in other cultures. Many complementary therapies can be used by people with diabetes, but there are associated risks that need to be considered.

The people at the centre of care

President's editorial