Future Directions

English

A future of glucose-responsive insulin secretion: bionics versus nature

people with diabetes constantly walk a tight rope between strict glucose control to prevent complications and hypoglycaemia. Too often, slight miscalculations result in hypoglycaemia, which can be at best embarrassing and irritating, and may cause injury or even death.

Looking for new pharmacological treatments for type 2 diabetes

Type 2 diabetes is a heterogeneous disease characterized by multiple pathogenic defects. Impaired insulin secretion and insulin action (insulin resistance) are well-recognized major mechanisms contributing to the development of diabetes. In the past years, intensive research has much improved our understanding of the molecular mechanisms leading to defects of beta-cell function and impaired ability of insulin to promote glucose uptake in muscle and adipose tissue. More recently, other organs have been shown to play a role in the abnormalities of glucose homeostasis.

IDF first to address the question: is bariatric surgery good for diabetes?

Last year, ID F’s Taskforce on Epidemiology and Prevention of Diabetes convened a working group to review the role of surgery in the treatment and prevention of type 2 diabetes. Bariatric surgery, in which the gastrointestinal tract is operated on with the intention of achieving weight loss, has been shown to have significant metabolic benefit. In December last year, 20 people representing all the ID F regions, and different clinical disciplines, met at ID F’s headquarters to review the available evidence and consider the potential of the procedures for people with diabetes.

One Year to the UN's NCDs : IDF's roadmap

The countdown to the UN Summit on NC Ds has begun. With exactly one year to go, IDF launched the Diabetes Roadmap for the UN High-Level Summit on NCDs, which will ensure that this once-in-ageneration global platform moves the world from rhetoric to action on diabetes. Ann Keeling reports.

A Champion for NCDs: an interview with George Alleyne

Diabetes Voice had the pleasure of speaking with Sir George Alleyne shortly after the UN Department of Public Information/Non-Governmental Organization (DPI/NGO) conference took place in Melbourne between 30 August and 1 September 2010 on the theme Advance Global Health: Achieve the MDGs. Sir George highlighted the central role of non-communicable diseases (NCDs) in global health and development in his keynote speech at the close of the event.

IDF Guide to National Diabetes Programmes - new needs, new approach

We live in difficult but very exciting times: IDF has never been better organized or more powerful in its influence on global health policy at the highest level. The 2006 UN Resolution on Diabetes and the central role of IDF in bringing about the UN General Assembly decision in May this year to hold a UN Summit on Non-Communicable Diseases in September 2011 are proof of IDF’s effectiveness on the world stage.

Mobilizing on women and diabetes for global development

For three decades, ambitious commitments have been made at the global level to promote gender equality and empower women. But the translation into action of the commitments pledged in the Convention of the Elimination of All Forms of Discrimination Against Women, the Beijing Platform for Action and the Millennium Development Goals has been less impressive. Inequality between women and men and girls and boys remains pervasive, particularly in lowand middle-income countries.

IDF and the global NCD alliance: united for health and development

Non-communicable diseases, including diabetes, heart disease and cancers, cause 8 million premature deaths every year in low- and middle-income countries. The World Health Organization estimates that global deaths from these diseases will continue to rise over the next 10 years, with the African region expected to see the highest relative increase (27%). An increasing body of evidence shows that the human and financial impact of disease is undermining the achievement of the Millennium Development Goals.

Who's who in the global NCD alliance?

The global community is waking up to the potentially calamitous impact across all regions of diabetes and other non-communicable diseases (NCDs). The numbers are alarming. In 2005, chronic diseases, including cardiovascular disease, diabetes and cancers, accounted for 60% of deaths worldwide and almost half of the global burden of disease. Today, cardiovascular disease is the world's number one cause of mortality: 17 million deaths each year. The number of people with diabetes is set to rise from the current 238 million to 440 million by 2030.

The untold burden of the non-communicable disease epidemic

The recent Global Risks 2010 report issued by the World Economic Forum identifies chronic non-communicable diseases (NCDs) as one of the most important threats to the world’s agenda and a severe risk for global economic loss. NCDs, including diabetes, cardiovascular and respiratory diseases and cancer, are already extraordinarily costly to governments and the private sector, crowding out essential monies for needed government services and reducing profits.

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