Cardiovascular risk in type 2 diabetes patients: an innovative dynamic prediction model (ST12-032)

Main institution:
The EMGO Institute for Health and Care Research (The Netherlands)

Other institution:
The National Institute for Health and Care Research (The Netherlands)

Principal investigator:
Giel Nijpels

Other investigators:
Amber van der Heijden; Jacqueline Dekker; Hendriek Boshuizen; Talitha Feenstra; Caroline Baan

Location of the project:
Amsterdam, The Netherlands

Amount allocated:
USD 65.000

June 1, 2012 - July 1, 2015


Medical and lifestyle interventions can reduce diabetes complications. A key component for targeting these interventions is the assessment of an individual's risk of developing a complication within a defined time period, using prediction models. Current models are flawed, however, implying both undertreatment and overtreatment by targeting the wrong persons for prevention of complications.

This project will result in an improved and practically applicable prediction model for cardiovascular complications in type 2 diabetes patients. Using this model, patients can be better informed about their prognosis and treatment plans can be better tailored leading to a reduction in complications and treatment costs.

Results to date

EASD 2014, Vienna (Austria), September 2014 (3 posters also published in Diabetologia 57 suppl 1.2014)

"Distinct HbA1c trajectories in a type 2 diabetes cohort", Acta Diabetologica, 2015, April 2015, Volume 52, Issue 2, pp 267-275
"Real-world evidence of suboptimal blood pressure control in patients with type 2 diabetes", Journal of Hypertension, 2015, 33 (in press)


BRIDGES (Bringing Research in Diabetes to Global Environments and Systems) is a programme initiated by the International Diabetes Federation, and supported by an educational grant from Lilly Diabetes.